Curcumin Extract is a potent antioxidant that depletes levels of substance P, a neuropeptide associated with pain sensation, to promote comfort of the joints and cartilage. Curcumin also helps maintain platelet aggregation levels that are already within normal range, and supports arachadonic acid metabolism to help maintain a healthy inflammatory balance.* The addition of Bioperine® piperine from Black Pepper Extract increases the bioavailability of the Curcumin by 2,000%.* Vital Nutrients exclusively uses Curcumin Extract specially produced without 1,2-dichloroethane, to ensure the products are free of these toxic solvent residues.